Katja von Hoff is Clinical Consultant and Associate Professor of Paediatric Oncology at Aarhus University Hospital, Denmark. She further holds an affiliation at the Charité Universitätsmedizin. Her clinical and research focus is on paediatric malignant tumors of the central nervous system. She has been involved in the design and conduct of multicentre, international clinical trials on embryonal tumours and ependymoma. In the recent years, she has focused on clinical research on rare embryonal tumours of the CNS, conceding the dilemma of lacking prospective clinical data and treatment standards for the newly acknowledged molecularly defined tumor types. Given the rarity of these diseases, she is working on interdisciplinary and multi-centre collaborations to gain further insights and clinically applicable knowledge. She is an author or co-author of several relevant publications in this field and was a co-author on the 2021 WHO Classification of Tumours of the Central Nervous System. She has chaired the ESCP (European Standard Clinical Practice) guidelines on rare embryonal and sarcomatous tumours of the central nervous system and chairs a working group on these tumor types within the SIOP-E (European Society for Paediatric Oncology).